多階層をつなぐ4D細胞計測の次世代化による細胞動態の理解と操作 : 研究発表一覧

原著論文（主なもの）:
2015 | 2014 | 2013
総説（主なもの）:
2015 | 2014 | 2013
国際会議招待講演・会議・シンポ・ワークショップ（主なもの）:
2015 | 2014 | 2013
プレスリリース:
2015 | 2014 | 2013
特許（予定を含む）:
2015 | 2014 | 2013

原著論文（主なもの）

2015

T. Tsutsui, et al., Plant Cell Physiol. 56:1073-1083 (2015).
M. Iwai, et al., Plant Signal. Behav. 10:e1022014 (2015).
K. Nakanishi, et al., FASEB J. 29:2137-2149 (2015).
A. Baral, et al., Plant Cell 27:1297-1315 (2015).
T. Kanazawa, et al., Plant Cell Physiol. 57:307-324.
M. Sunada, et al., J. Plant Res. 129:93-102 (2016).
K. Ishii, et al., PLOS ONE 10: e0140287 (2015).
E. Ito, et al., Plant Biotech. in press.
T. Haraguchi, et al., Plant Cell Physiol. in press.
J. Cui, et al., Bioorg. Med. Chem. 2015, 23, 2989-2994.
V. Mackel, et al., Journal of Physics: Conference Series 635 (2015) 042006
N. Puttaraksa, et al., Nuclear Instruments and Methods in Physics Research B 348 (2015) 127–130
V. Mäckel, et al., REVIEW OF SCIENTIFIC INSTRUMENTS 86, 085103 (2015)
Yilmaz N, Kobayashi T., ACS Nano 9, 7960-7967 (2015).
Ueda Y, et al., Sci Rep 5, 12960 (2015).
Bhat HB, et al., FASEB J 29, 3920-3934 (2015).
Murate M, et al., J Cell Sci 128, 1627-1638 (2015).
Makino A, et al., FASEB J 29, 477-493 (2015).
Q. Song, et al., Rev. Sci. Instrum., 86, 083701 (2015).
N. Yamashita, et al., Journal of Biomedical Optics, Vol. 20(10):101206:1-18 (2015).
森田正彦, et al., "生物画像処理のためのクラウド型システム", Medical Imaging Technology, Vol. 33(3), pp. 112-117 (2015).
Hama H, et al., Nat. Neurosci., 18 (10): 1518-1529 (2015).
Tsutsui H, et al., Mol. Cell, 58 (1), 186-193 (2015).
Guy AT, et al., Science 349: 974-977 (2015).
Wada F, et al., Cell Reports (doi: 10.1016/j.celrep.2016.04.021.) in press.
Hanezzo E., et al., Proc. Natl. Acad. Sci. U.S.A. 112: 8620–8625 (2015).
Otani T., et al., Development 142: 2338-2351 (2015).
Kato, K., et al., Nature Communications 7, Article number: 11141 doi:10.1038/ncomms11141 (2016).
Takayama, J., Onami, S., Cell Rep. 15, 625-637 (2016)
Atupelage, C., et al., Proceedings of the International Conference on Biology and Biomedical Engineering, 27-32 (2015).
Han, X., et al., Proceeding of the 3rd Asian Conference on Pattern Recognition (2015).
Chinen T, et al., Nat Commun. 6:8722 (2015).
Hayashi S, Okada Y., Mol. Biol. Cell., 26:1743-51 (2015).
Takai A, et al., Proc. Natl. Acad. Sci. U S A. 112:4352-6 (2015).
Ohyanagi T, et al., Chem. Commun., 51(80):14836-9 (2015).
Kitano M., et al., Proc. Natl. Acad. Sci. U.S.A. 113, 1044-1049 (2016).
Hashimoto, M., et al., J. Immunol. 196, 1832-184 (2016).
Daniels N.J., et al., Mucosal Immunol. 9, 229-239 (2016).
Lin W.W., et al., Cell Rep. 13, 1-16 (2015).
Moindrot, B., et al., Cell Rep. 12, 562-72 (2015).
Yuan-Hsiang Chang, et al., Accepted as a contributed paper for the 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (2016b).
Takemoto, T., et al., Genes to Cells, in press.
Nakao, H., et al., Genesis, Vol54, 2, P.65-77, doi:10.1002/dvg.22914 (2016).
Kurimoto, K., et al., Cell Stem Cell, Vol.16, 5, P.517-532, doi:10.1016/j.stem.2015.03.002 (2015).
Nakatsu, Y., et al., The Journal of Biological Chemistry,. Vol.290, 40, P.24255-24266, doi:10.1074/jbc.M115.658559 (2015).
Tsujimura, K., et al., Cell Reports, Vol.12, 11, P.1887-1901, doi:10.1016/j.celrep.2015.08.028 (2015).
Sato, S., et al., PLoS One, Vol.10, 8, e0136666, doi:10.1371/journal.pone.0136666 (2015).
Hiramuki, Y., et al., PLoS One, Vol.10, 6, e0130436, doi:10.1371/journal.pone.0130436 (2015).
Imai, Y., et al., PLoS Genetics, Vol.11, 9, e1005503, doi:10.1371/journal.pgen.1005503 (2015).
Lee, M. S., et al., Developmental Biology, Vol.400, 2, P.248-257, doi:10.1016/j.ydbio.2015.02.009 (2015).
Nojiri, T., et al., Proceedings of the National Academy of Sciences of the United States of America, Vol.112, 13, P.4086-4091, doi:10.1073/pnas.1417273112 (2015).

2014

T. Uemura, et al., Plant Cell Physiol. 55, 694-670 (2014).
Y. Hashiguchi, et al., Plant Cell Physiol. 55, 811-822 (2014).
M. Fujiwara, et al., Plant Cell Physiol. 55, 781-789 (2014).
H. Kawai-Toyooka, et al., Eukaryotic Cell 5, 648-656 (2014).
K. Kurokawa, et al., Nat. Commun. 5, 3653 (2014).
T. Haraguchi, et al., J. Biol. Chem. 289, 12343-12355 (2014).
S. Miyagishima, et al., Nat. Commun. 5, 3807 (2014).
Y. Cui, et al., Plant Cell 26, 2080-2097 (2014).
K. Ebine, et al., Curr. Biol. 24, 1375-1382 (2014).
S. Naramoto, et al., Plant Cell 26, 3062-3076 (2014).
M. Iwai, et al., Nat. Plants 1, 14008, 2015.
M. Fujimoto, et al., Plant Cell Physiol. 56:287-298, 2015.
T. Tsutsui, et al., Plant Cell Physiol. in press.
M. Iwai, et al., Plant Signal. Behav. in press.
K. Nakanishi, et al., FASEB J. in press.
A. Baral, et al., Plant Cell in press.
Takai A, et al., Proc Natl Acad Sci USA. 112: 4352-4356, 2015.
Hayashi S, Okada Y, Mol Biol Cell in press, 2015.
Okada Y, Nakagawa S, Meth Mol Biol 1262: 21-35, 2015.
Uno S, et al., Nat Chem, 6: 681-689, 20143.　
Chiba K, et al., Mol Biol Cell 25: 3569-3580, 2014.
H Yaginuma, et al., Sci. Rep. 4, 6522; DOI:10.1038/srep06522, 2014.
Kasahara K, et al., Nat Commun. 2014 Oct 1;5:5081. doi: 10.1038/ncomms6081, 2014.
Jones C, et al., Dev Biol. 2014 Nov 1;395(1):62-72. doi: 10.1016/j.ydbio.2014.08.029. Epub 2014, Sep 10, 2014.
Ito H, et al., Mol Psychiatry. 2014 Jul 29. doi: 10.1038/mp.2014.69. [Epub ahead of print], 2014.
Mora-Bermudez F, et al., eLife. 2014 Jul 4;3. doi: 10.7554/eLife.02875, 2014.
Kondo T, et al., Development Growth and Differentiation 56: 86-91, 2014.
Dong, B., et al., Cell Reports 7:4, 941-950, 2014.
Dong B., et al., Development 141:21, 4104-4109, 2014.
Miao G., Hayashi S, Developmental Dynamics 244:479-487, 2014.
Shinohara, H., et al., Science, 344, 760-764, 2014.
Morita, S.-i., et al., Biophys. J. 107, 2221-2229, 2014.
Park, H., et al., FASEB J. 29, 837-848, 2015.
Arata, Y., et al., Frontiers in Physiol. DOI: 10.3389/fphys.2014.00529 (1-11), 2015.
Takanezawa, S., et al., Biophys. J. in press, 2015.
Matsunaga S, et al., Langmuir in press, 2015.
Arita Y, et al., Chem Biol in press, 2015.
Murate M, et al., J Cell Sci 128, 1627-1638, 2015.
Lee S, et al., EMBO J 34, 669-688, 2015.
Makino A, et al., FASEB J 29, 477-493, 2015
Hiroyuki Y, et al., Bioorg. Med. Chem. Lett. 2015, 25, 664-667, 2015.
Jun Ando, et al., Proc. Nat. Acad. Sci. 2015, 112, 4558-4563. [プレスリリース]
Natsuaki Y, et al., Nat Immunol 15,1064-9, 2014.
Moriyama S, et al., J Exp Med 211,1297-305, 2014.
Oikawa M, et al., Epigenetics in press, 2014.
Yukawa M, et al., PLoS One 9, e92689, 2014.
Kono H, et al., DNA Research in press, 2014.
Kitamura T, et al., Science 343, 896-901, 2014.
Sato A, et al., Mutation Research 762, 17-23, 2014.
Shiura H, et al., PLoS One. 9, e95750, 2014.
Kimura T, et al., Stem Cells 33, 45-55, 2015.
Sugimoto M, et al., Stem Cell Reports in press, 2015.
Inoue K, et al., Scientific Reports in press, 2015.
M. Morita, et al., International Journal of Networking and Computing, Vol. 4, No. 2, pp. 369-391, 2014.
Kuwahara A, et al., Nat Commun. 6, 6286, 2015.
Okuda S, et al., Biomech Model Mechanobiol. 14, 413, 2014.
Kyoda, K., et al., Bioinformatics 31, 1044-1052, 2015.

2013

F. Almar, et al., Curr. Opin. Chem. Biol. 17:708-715, 2013.
H. Yamakoshi, et al., Chem. Comm. 50:1341-1343, 2014.
T. Yamaguchi, et al., Chem. Sci. 5:1021-1029, 2014.
T. Kadoshima, et al., Proc .Natl. Acad. Sci. U. S. A. 110:20284-20289, 2013.
H. Inomata, et al., Cell 153:1296-1311, 2013.
S. Okuda, et al., Biomech. Modeling Mechanobiol. 12:987-996, 2013.
H. Shiura, et al., PLoS One. 9:e95750, 2014.
T. Abe and T. Fujimori, et al., Dev. Growth Diff. 55:390-405, 2013.
Y. Imuta, et al., Genesis 51:210-218, 2013.
A. Nakashima, et al., Cell 154:1314-1325, 2013.
M. Sakaguchi, et al., Nat. Commun. 4:1398, 2013.
D. Takao, et al., Dev. Biol. 376:23-30, 2013.
K. Tsujino, et al., Genes Cells 18 575-588, 2013.
M. Iwai, et al., Sci. Rep. 3:2833, 2013.
M. Tominaga, et al., Dev. Cell 27:345-352, 2013.
Y. Suda and A. Nakano. Proc. Natl. Acad. Sci. U. S. A. 110:18976-18981, 2013.
R. Hirata, et al., J. Biol. Chem. 288:37057-37070, 2013.
M. Iwai, et al., Sci. Rep. 4:3768, 2013.

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総説（主なもの）

2015

Akihiko Nakano, Nature 521:427-428 (2015).
David G. et al., Plant Physiol. 168:393-406 (2015).
闐闐孝介、袖岡幹子, CSJカレントビュー　生物活性分子のケミカルバイオロジー, 155-162 （2015）.
Kishimoto T, Ishitsuka R, Kobayashi T. Biochim. Biophys Acta in press (2016).
Yilmaz N, Kobayashi T, Biophys Acta 1858, 500-511 (2016).
Yamaji-Hasegawa A, Hullin-Matsuda F, Greimel P, Kobayashi T., Biochim. Biophys Acta 1858, 576-592 (2015).
Murate M, Kobayashi T, Chem Phys Lipids 194, 58-71 (2015).
磯部圭佑，緑川克美，日本レーザー医学会誌，36，210-215　(2015)．
Dong B., Hayashi S. Current Opinion in Genetics & Development 32:129-134 (2015).
Kondo T., Hayashi S. Develp. Growth and Diff. 57: 313-323 (2015).

2014

Y. Ito, et al., Intl. Rev. Cell Mol. Biol. 310, 221-287, 2014.
A. Nakano, Nature in press.
D. G. Robinson, et al., Plant Physiol. in press.
岡田康志, et al., 実験医学, 32:3074-3076, 2014.
岡田康志, パリティ 29:37-39, 2014.
岡田康志, 実験医学, 32:2623-2629, 2014.
Dong B., Hayashi S, Current Opinion in Genetics & Development 32:129-134, 2015.
林茂生, 董波, 細胞工学, 33:6 pp. 623-627, 2014.
林茂生, et al., 実験医学別冊今すぐ始めるゲノム編集, pp.130-139, 2014.
近藤武史, 林茂生, 実験医学, 33:3 pp.411-417, 2015.
Pack, C.-G., et al., pp.153-170. Cornea, A. and Conn, P. M. eds. Elsevier, 2014.
磯部圭佑, 緑川克美, 光学, 44, 18-22, 2015.
V. Mackel, et al., Rev. Sci. Instruments. 85, 014302, 2014.
池田理恵子, 阿部訓也, 実験医学別冊次世代シークエンス解析スタンダード二階堂愛・編集, 羊土社, page 165-172, 2014.
鈴木雅子, 阿部訓也, 実験医学別冊次世代シークエンス解析スタンダード二階堂愛・編集, 羊土社, page 173-181, 2014.
Azuma, Y., Onami, S., Biomed. Eng. Lett., 4, 328-337, 2014.
大浪修一, 画像ラボ 25(8), 12-18, 2014.
大浪修一, In 生命のビッグデータ利用の最前線, 植田充美監修, 株式会社シーエムシー出版, pp. 218-234, 2014.

2013

T. Abe, et al., Methods Mol. Biol. 1052:101-108, 2013.
L. Cao and K. Abe. "Frontiers in Intravital Microscopy" ed. Robert Weigert (Springer), in press, 2014.
A. Nakano. Conf. Proc. IEEE Eng. Med. Biol. Soc. 2013:133-135, 2013.
K. Kurokawa, et al., Methods Cell Biol. 118:235-242, 2013.

最上部へ移動

国際会議招待講演・会議・シンポ・ワークショップ（主なもの）

2015

A. Nakano, Gordon Research Conference on Molecular Membrane Biology. Andover, NH, USA, July 12-17 (13), 2015.
A. Nakano, Symposium “Spatial Distribution of Cellular Processes,” 23rd Congress of the International Union of Biochemistry and Molecular Biology, Foz do Iguaçu, Brazil, August 24-28 (26), 2015.
A. Nakano, Commemorative Symposium for the 31st International Prize for Biology “New horizons in life science through advances in cell biology,” Kyoto, Japan, December 5-6 (5), 2015.
M. Sodeoka, Pacifichem2015, Honolulu, USA, 15 December (2015).
K. Dodo, 2016 Queenstown Molecular Biology Meetings, Shanghai, 17 March （2016）.
Kobayashi T., Gordon Research Conference on Glycolipid and Sphingolipid Biology. March 6-11 2016, Lucca, Italy.
Kobayashi T., Sphingonet’s International Colloquium. Jan 27-29 2016 Amsterdam, Netherland.
Kobayashi T., 11th GERLI Lipidomics Meeting. Oct 25-28, 2015, Strasbourg France.
Y. Maeda, et al., CLEO-Europe /QLEC 2015, CL-4.4-TUE, Munich Germany, June (2015).
A. Miyawaki, Biophysical Society Thematic Meeting on New Biological Frontiers Illuminated by Molecular Sensors and Actuators, Keynote speaker, 2015.6.28, Taipei, Taiwan.
Kamiguchi, H., The 3rd International Symposium on Glyco-Neuroscience, Awaji, 2016.1.15.
Eiraku, M., CRTD/ISSCR International Symposium, 2016.2.1.
Onami, S., CREST International Symposium on Big Data Application, Tokyo, Japan, Mar 4-5, 2016.
Onami, S., QBiC Symposium 2015: High-Dimensional Data for the Design Principles of Life, Suita, Japan, Aug 24-26, 2015.
Takayama J., Onami S., 2015 American Society for Cell Biology Annual Meeting, San Diego, Dec 12-16, 2015.
Tohsato, Y., Ho, K., Kyoda, K., Onami, S.: SSBD: an integrated database of quantitative data and microscopy images of biological dynamics. 10th Annual OME Users Meeting, Paris, Jun 2-3, 2015.
Atupelage, C., et al., The 2015 International Conference on Biology and Biomedical Engineering, Vienna, Austria, Mar 15-17, 2015.
Okada Y., Pacifichem 2015, Life at Small Copy Numbers, Honolulu, 2015.12.20.
Okada Y., The 2nd East Asia Microscopy Conference, Himeji, 2015.11.25.
Okada Y., “Dissecting kinesin regulation through single molecule in cellulo measurements” Janelia Conference, 2015.
Okada Y., 9th Asian Biophysics Association Symposium, 2015.
Okada T., The 44th Annual Meeting of Japanese Society for Immunologists, GlaxoSmithKline K. K. Clinical Seminar (Sapporo, Japan) November, 2015.
Ohno, H., 14th Transplantation Science Symposium (Lorne, Australia) November, 2015.
Okada T., The 10th Invited Immunologist Seminar at The Shonan Research Center of Takeda Pharmaceutical Company (Fujisawa, Japan) October, 2015.
Okada T., The 65th Annual Meeting of the Japan Society for Cell Biology (Tokyo, Japan) July, 2015.
Ohno, H., International Scientific Conference on Probiotics and Prebiotics 2015 (Budapest, Hungary) June, 2015.
Ohno, H., EMBO Workshop “Cellular synapsis for cell-cell signalling” (Madrid, Spain) May, 2015.
Furuta, Y., Genomic Analysis and Editing Workshop, 8th Meeting of the Latin American Society for Developmental Biology, October 2015, Santos, Brazil.

2014

A. Nakano, International ERATO Higashiyama Live-Holonics Symposium, Nagoya, Japan, September 10, 2014.
宮脇敦史, 第37回内藤コンファレンス, 2014.7.17.
宮脇敦史, Zeiss User Meeting 2014.11.26.
Atsushi Miyawaki, 17th A-IMBN Annual Conference 2014.12.1.
Atsushi Miyawaki, 「細胞機能と分子活性の多次元蛍光生体イメージング」国際シンポジウム, 2015.1.26.
Yasushi Okada, International Symposium on Multi-dimensional Fluorescence Live Imaging of Cellular Functions and Molecular Activities, 2015.1.27.
Akira Takai, et al., American Society for Cell Biology/International Federation for Cell Biology Meeting, 2014.12.6-10.
Okada, Y, 2nd Asian Image Sensors and Imaging Systems Symposium, 2014.12.1-2.
Okada, Y, International Symposium - Imaging the inner life of cells, 2014.11.21.
Okada, Y, Tokyo ATPase Workshop, 2014.6.2.
Fumio Matsuzaki, Cortical Developmet Conference 2014, "Neural Stem Cells to Neural Circuits", 2014.5.22-25.
Fumio Matsuzaki, Conference Jacques Monod2014, "Cell cycle: bridging scales in cell division", 2014.10.11-15.
Fumio Matsuzaki, Workshop ‘Neural Progenitors: In Vivo Cellular Approaches to Novel Biological Problems’ the 2014 American Society of Cell Biology meeting 2014.12.6-10.
Fumio Matsuzaki, 2nd UK-JAPAN Workshop on Neural Epigenetics: Epigenetics and transcription in the brain towards single cell analysis, 2014.12.15-16.
Fumio Matsuzaki, Mini-workshop on Neural Development, 2014.12.17.
Maeda, R., et al., Single Protein Dynamics in Cellulo SPDC 2014, 2014.4.24.
Sako, Y., Single Protein Dynamics in Cellulo SPDC 2014, 2014.4.25.
Sako, Y., The Joint Annual Meeting of The Japanese Society for Mathematical Biology and The Society for Mathematical Biology 2014, 2014.7.30.
Hiroshima, M. and Sako, Y., The Joint Annual Meeting of the Japanese Society for Mathematical Biology and the Society for Mathematical Biology 2014, 2014.7.30.
Kobayashi T., Pore-forming toxins (PFT2014), 2014.8.28-30.
磯部圭佑, 緑川克美, 応用物理学会・量子エレクトロニクス研究会「バイオ・メディカルフォトニクスII～量子エレクトロニクスはいかに医生物学に貢献できるか～」, 2014.12.
Mikiko Sodeoka, 3rd Asian Chemical Biology Conference, Singapore.
Okada T., Naito Conference: Bioimaging-a paradigm shift for the life sciences, July 2014.
Okada T., Australasian Society for Immunology Annual Scientific Meeting 2014, December 2014.
Okada T., International Symposium on Multi-dimensional Fluorescence Live Imaging of Cellular Functions and Molecular Activities, January 2015.
阿部訓也, 第28回環境ホルモン学会, 2014.6.19.
Kyoda, K., et al., International Workshop on Quantitative Biology 2014, Sep 13, 2014.
Atupelage, C., et al., The 2015 International Conference on Biology and Biomedical Engineering, Mar 15-17, 2015.
Tohsato, Y., et al., Bioimage Informatics 2014 (BII 2014), Oct 8-10, 2014.
Fujita, M., Onami, S., Cell Biology and Gene Expression Meeting in association with The 6th Asia-Pacific C. elegans Meeting, Jul 15-19, 2014.
Ho, K. H. L., et al., Cell Biology and Gene Expression Meeting in association with The 6th Asia-Pacific C. elegans Meeting, Jul 15-19, 2014.
Azuma Y., Onami S., GIW/ISCB-Asia 2014, Dec 15-17, 2014.（ポスター発表）
Fujita M., Onami S., The 2014 ASCB/IFCB Meeting, Dec 6-10, 2014. （ポスター発表）
Onami, S., CSHL Meeting on Biological Data Science, Cold Spring Harbor Laboratory, Cold Spring Harbor, Nov 5-8, 2014. （ポスター発表）
Ho, K., et al., The 15th International Conference on Systems Biology (ICSB), Sep 14-18, 2014. （ポスター発表）
Tohsato, Y., et al., 9th Annual OME user's meeting, Jun 5-6, 2014. （ポスター発表）

2013

M. Morita. International Symposium on Computing and Networking, Matsuyama, Japan, 2013.
A. Miyawaki. 16th Medical Image Computing and Computer Assisted Intervention, Nagoya, Japan, 2013.
A. Miyawaki. 26th International Conference on Photochemistry, Leuven, Belgium, 2013.
A. Miyawaki. Cold Spring Harbor Asia Conference on Francis Crick Symposium on Neuroscience: The Changing Brain, Suzhou, China, 2013.
Y. Sasai. Hans Sigrist Symposium, Bern, Germany, 2013.
Y. Sasai. Gurdon Institute Seminar, Cambridge, England, 2013.
Y. Sasai. IMBASymposium, Vien, Austria, 2013.
A. Nakano and K. Kurokawa. Golgi Apparatus Symposium. Bad Ischl, Austria, 2013.
A. Nakano. Institut Jacques Monod Seminar. Paris, France, 2013.
A. Nakano. Max-Planck Inst. for Plant Breeding Seminar. Cologne, Germany, S, 2013.

最上部へ移動

プレスリリース

2015

細胞まるごと三次元画像データの自動解析法を開発
－画像処理と数理計算の融合により巨大データを精密に解く新手法－ (2015/11/5)

2014

脂質の分布をありのままに観察する新技術～小さな目印をつけて直接観察することに成功～ (2015/3/31)

2013

最上部へ移動

特許（予定を含む）

2015

A. Nakano and A. Ichihara, “Drive control method for objective lens and fluorescence microscope system”, United States application number 14/915.210, February 26, 2016.

2014

中野明彦, 市原昭, "対物レンズの駆動制御方法及び蛍光顕微鏡システム", 国際出願番号PCT/JP2014/00434, 書類番号24779, 2014.8.25.
磯部圭佑, 緑川克美, "波面歪み量測定装置，波面補償装置，光学測定装置，および方法", 特願2014-266374, 出願日 2014.12.26.

2013

特願2013-175477「対物レンズの駆動制御方法及び蛍光顕微鏡システム」中野明彦、市原昭 (出願 2013/8/27）
特願2013-242394「終脳又はその前駆組織の製造方法」笹井芳樹、門嶋大輔 (出願 2013/11/22）

最上部へ移動